Buffalo Museum of Science location). Generally, it opens up at 10 AM and shuts at 5 PM, however weekends may have prolonged hours Are There Any Admission Price Cuts Offered? Yes, you can locate admission discount rates at the museum. Enjoy your go to! Is the Museum Mobility Device Accessible? https://simoncxpuu.webbuzzfeed.com/35531660/the-buffalo-museum-of-science-hosts-activities-that-educate-visitors