Last of all, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive method, which can reduce the dose of every part by sixty% for postoperative analgesia. Clonidine treats large blood pressure by stimulating α2 receptors from the brainstem, which decreases peripheral vascular resistance, reducing hypertension. https://www.proleviate.com/post/the-new-pain-killer-conolidine